Leanne Manas Weight Loss - Lack of sleep can cause you to store more belly fat and may also cause ghrelin to increase and leptin to decrease. Omega 3 fatty acids are linked to decreased hunger. Often appetite can spike when you are slightly dehydrated. As your level of fitness increases, you can start to incorporate more high intensity training and weight lifting to increase results. The hardest part about losing 50 pounds or more can sometimes be getting started.